Severe infections emerge from commensal bacteria by adaptive evolution

Bacteria responsible for the greatest global mortality colonize the human microbiota far more frequently than they cause severe infections. Whether mutation and selection among commensal bacteria are associated with infection is unknown. We investigated de novo mutation in 1163 Staphylococcus aureus...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Young, Bernadette C, Wu, Chieh-Hsi, Gordon, N Claire, Cole, Kevin, Price, James R, Liu, Elian, Sheppard, Anna E, Perera, Sanuki, Charlesworth, Jane, Golubchik, Tanya, Iqbal, Zamin, Bowden, Rory, Massey, Ruth C, Paul, John, Crook, Derrick W, Peto, Timothy E, Walker, A Sarah, Llewelyn, Martin J, Wyllie, David H, Wilson, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Microbiology and Infectious Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736351/
https://ncbi.nlm.nih.gov/pubmed/29256859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30637
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