Retinoic acid deficiency leads to an increase in spermatogonial stem number in the neonatal mouse testis, but excess retinoic acid results in no change

The onset of spermatogenesis occurs in response to retinoic acid (RA), the active metabolite of vitamin A. However, whether RA plays any role during establishment of the spermatogonial stem cell (SSC) pool is unknown. Because designation of the SSC population and the onset of RA signaling in the tes...

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Bibliographic Details
Published in:Dev Biol
Main Authors: Agrimson, Kellie S., Oatley, Melissa J., Mitchell, Debra, Oatley, Jon M., Griswold, Michael D., Hogarth, Cathryn A.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736010/
https://ncbi.nlm.nih.gov/pubmed/29037932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.10.002
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