Brain Amyloid-β and Slow Gait in Older Adults without Dementia: Influence of Cognition and APOE-ε4 Genotype

IMPORTANCE: Motor slowing appears in preclinical Alzheimer’s disease (AD), progresses with AD progression and is associated with AD pathology at autopsy. Whether amyloid-beta (Aβ) is associated with gait speed in dementia free elders and whether cognition and apolipoprotein E (APOE) ε4 influence thi...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Nadkarni, Neelesh K., Perera, Subashan, Snitz, Beth E., Mathis, Chester A., Price, Julie, Williamson, Jeff D., DeKosky, Steven T., Klunk, William E., Lopez, Oscar L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735996/
https://ncbi.nlm.nih.gov/pubmed/27842173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.3474
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