Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

BACKGROUND: Non-adherence has been associated with reduced graft survival. The aim of this study was to investigate the immunological mechanisms underlying chronic renal allograft rejection using a model of non-adherence to immunosuppressive therapy. We used a MHC (major histocompatibility complex)...

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Publicat a:BMC Immunol
Autors principals: Kühne, Louisa, Jung, Bettina, Poth, Helen, Schuster, Antonia, Wurm, Simone, Ruemmele, Petra, Banas, Bernhard, Bergler, Tobias
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735914/
https://ncbi.nlm.nih.gov/pubmed/29258420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0236-6
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