Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial

BACKGROUND: We have previously shown that radiotherapy (RT) augments natural killer (NK) functions in pre-clinical models of human and mouse cancers, including sarcomas. Since dogs are an excellent outbred model for immunotherapy studies, we sought to assess RT plus local autologous NK transfer in c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunother Cancer
Päätekijät: Canter, Robert J., Grossenbacher, Steven K., Foltz, Jennifer A., Sturgill, Ian R., Park, Jiwon S., Luna, Jesus I., Kent, Michael S., Culp, William T. N., Chen, Mingyi, Modiano, Jaime F., Monjazeb, Arta M., Lee, Dean A., Murphy, William J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735903/
https://ncbi.nlm.nih.gov/pubmed/29254507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0305-7
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