Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients

BACKGROUND: Mitochondrial dysfunction may represent a pathogenic factor in Huntington disease (HD). Physical exercise leads to enhanced mitochondrial function in healthy participants. However, data on effects of physical exercise on HD skeletal muscle remains scarce. We aimed at investigating adapta...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Mueller, Sandro Manuel, Gehrig, Saskia Maria, Petersen, Jens A., Frese, Sebastian, Mihaylova, Violeta, Ligon-Auer, Maria, Khmara, Natalia, Nuoffer, Jean-Marc, Schaller, André, Lundby, Carsten, Toigo, Marco, Jung, Hans H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735536/
https://ncbi.nlm.nih.gov/pubmed/29258585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-017-0740-z
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