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Dual Level Statistical Investigation of Equilibrium Solubility in Simulated Fasted and Fed Intestinal Fluid

[Image: see text] The oral route is the preferred option for drug administration but contains the inherent issue of drug absorption from the gastro-intestinal tract (GIT) in order to elicit systemic activity. A prerequisite for absorption is drug dissolution, which is dependent upon drug solubility...

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Publicat a:Mol Pharm
Autors principals: Ainousah, Bayan E, Perrier, Jeremy, Dunn, Claire, Khadra, Ibrahim, Wilson, Clive G, Halbert, Gavin
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735376/
https://ncbi.nlm.nih.gov/pubmed/29072917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00869
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