Mitofusin 2 Promotes Apoptosis of CD4(+) T Cells by Inhibiting Autophagy in Sepsis

Apoptosis of CD4(+) T cells is a primary pathophysiological mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer membrane protein, has been confirmed to be associated with cellular metabolism, proliferation, and apoptosis. The function of...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Ying, Lan, Zhao, Guang-Ju, Wu, You, Ke, He-Liang, Hong, Guang-Liang, Zhang, Hui, Dong, Ning, Wu, Yao, Yao, Yong-Ming, Lu, Zhong-Qiu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735308/
https://ncbi.nlm.nih.gov/pubmed/29358849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4926205
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