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Mitofusin 2 Promotes Apoptosis of CD4(+) T Cells by Inhibiting Autophagy in Sepsis
Apoptosis of CD4(+) T cells is a primary pathophysiological mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer membrane protein, has been confirmed to be associated with cellular metabolism, proliferation, and apoptosis. The function of...
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| 出版年: | Mediators Inflamm |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5735308/ https://ncbi.nlm.nih.gov/pubmed/29358849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4926205 |
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