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MTHFR promoter hypermethylation may lead to congenital heart defects in Down syndrome
Altered global methylation levels revealed LINE-1 methylation in young mothers of Down syndrome (DS) compared to controls suggesting the possibility of impaired DNA methylation causing abnormal segregation of chromosome 21. Methylene Tetrahydrofolate Reductase (MTHFR) is one of the major enzymes of...
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| Publicado no: | Intractable Rare Dis Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Research and Cooperation Association for Bio & Socio-Sciences Advancement
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5735284/ https://ncbi.nlm.nih.gov/pubmed/29259859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2017.01068 |
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