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Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways

Influenza A viruses (IAV) can cause severe global pandemic outbreaks. The currently licensed antiviral drugs are not very effective and prone to viral resistance. Thus, novel effective and broadly active drugs are urgently needed. We have identified the cellular Raf/MEK/ERK signaling cascade as cruc...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Holzberg, Magdalena, Boergeling, Yvonne, Schräder, Tobias, Ludwig, Stephan, Ehrhardt, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735105/
https://ncbi.nlm.nih.gov/pubmed/29312159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02426
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