Mechanically stable solvent-free lipid bilayers in nano- and micro-tapered apertures for reconstitution of cell-free synthesized hERG channels

The self-assembled bilayer lipid membrane (BLM) is the basic component of the cell membrane. The reconstitution of ion channel proteins in artificially formed BLMs represents a well-defined system for the functional analysis of ion channels and screening the effects of drugs that act on them. Howeve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tadaki, Daisuke, Yamaura, Daichi, Araki, Shun, Yoshida, Miyu, Arata, Kohei, Ohori, Takeshi, Ishibashi, Ken-ichi, Kato, Miki, Ma, Teng, Miyata, Ryusuke, Tozawa, Yuzuru, Yamamoto, Hideaki, Niwano, Michio, Hirano-Iwata, Ayumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735097/
https://ncbi.nlm.nih.gov/pubmed/29255199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17905-x
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