Towards a Defined ECM and Small Molecule Based Monolayer Culture System for the Expansion of Mouse and Human Intestinal Stem Cells

Current ISC culture systems face significant challenges such as animal-derived or undefined matrix compositions, batch-to-batch variability (e.g. Matrigel-based organoid culture), and complexity of assaying cell aggregates such as organoids which renders the research and clinical translation of ISCs...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomaterials
Egile Nagusiak: Tong, Zhixiang, Martyn, Keir, Yang, Andy, Yin, Xiaolei, Mead, Benjamin E., Joshi, Nitin, Sherman, Nicholas E., Langer, Robert S., Karp, Jeffrey M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735007/
https://ncbi.nlm.nih.gov/pubmed/29120819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2017.10.038
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