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The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb

Microglia play important roles in perinatal neuro- and synapto-genesis. To test the role of microglia in these processes during adulthood, we examined the effects of microglia depletion, via treatment of mice with the CSF-1 receptor antagonist PLX5622, and abrogated neuronal-microglial communication...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Reshef, Ronen, Kudryavitskaya, Elena, Shani-Narkiss, Haran, Isaacson, Batya, Rimmerman, Neta, Mizrahi, Adi, Yirmiya, Raz
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734876/
https://ncbi.nlm.nih.gov/pubmed/29251592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30809
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