Efficacy of Augmentation of Cognitive Behavior Therapy With Weight-Adjusted D-Cycloserine vs Placebo in Pediatric Obsessive-Compulsive Disorder: A Randomized Clinical Trial

IMPORTANCE: Cognitive behavior therapy (CBT) among youth with obsessive-compulsive disorder (OCD) is effective, but many patients remain symptomatic after intervention. D-cycloserine, a partial agonist at the N-methyl-D-aspartate receptor in the amygdala, has been associated with enhanced CBT outcom...

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Udgivet i:JAMA Psychiatry
Main Authors: Storch, Eric A., Wilhelm, Sabine, Sprich, Susan, Henin, Aude, Micco, Jamie, Small, Brent J., McGuire, Joseph, Mutch, P. Jane, Lewin, Adam B., Murphy, Tanya K., Geller, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734635/
https://ncbi.nlm.nih.gov/pubmed/27367832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2016.1128
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