Investigating the safety and activity of the use of BTT1023 (Timolumab), in the treatment of patients with primary sclerosing cholangitis (BUTEO): A single-arm, two-stage, open-label, multi-centre, phase II clinical trial protocol

INTRODUCTION: Primary sclerosing cholangitis (PSC) is a progressive inflammatory liver disease characterised by relentless liver fibrosis and a high unmet need for new therapies. Preventing fibrosis represents an important area of interest in the development of vital new drugs. Vascular adhesion pro...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Arndtz, Katherine, Corrigan, Margaret, Rowe, Anna, Kirkham, Amanda, Barton, Darren, Fox, Richard P, Llewellyn, Laura, Athwal, Amrita, Wilkhu, Manpreet, Chen, Yung-Yi, Weston, Chris, Desai, Amisha, Adams, David H, Hirschfield, Gideon M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Gastroenterology and Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734279/
https://ncbi.nlm.nih.gov/pubmed/28674140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-015081
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