Single‐particle cryo‐EM—Improved ab initio 3D reconstruction with SIMPLE/PRIME

Cryogenic electron microscopy (cryo‐EM) and single‐particle analysis now enables the determination of high‐resolution structures of macromolecular assemblies that have resisted X‐ray crystallography and other approaches. We developed the SIMPLE open‐source image‐processing suite for analysing cryo‐E...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Reboul, Cyril F., Eager, Michael, Elmlund, Dominika, Elmlund, Hans
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Tools for Protein Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734274/
https://ncbi.nlm.nih.gov/pubmed/28795512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3266
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