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Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer’s Disease

BACKGROUND: Abnormal insulin signaling in the brain has been linked to Alzheimer’s disease (AD). OBJECTIVE: To evaluate whether cerebrospinal fluid (CSF) insulin levels are associated with cognitive performance and CSF amyloid-β and Tau. Additionally, we explore whether any such association differs...

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Pubblicato in:J Alzheimers Dis
Autori principali: Geijselaers, Stefan L.C., Aalten, Pauline, Ramakers, Inez H.G.B., De Deyn, Peter Paul, Heijboer, Annemieke C., Koek, Huiberdina L., OldeRikkert, Marcel G.M., Papma, Janne M., Reesink, Fransje E., Smits, Lieke L., Stehouwer, Coen D.A., Teunissen, Charlotte E., Verhey, Frans R.J., van der Flier, Wiesje M., Biessels, Geert Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734123/
https://ncbi.nlm.nih.gov/pubmed/29154275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170522
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