Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer’s Disease

BACKGROUND: Abnormal insulin signaling in the brain has been linked to Alzheimer’s disease (AD). OBJECTIVE: To evaluate whether cerebrospinal fluid (CSF) insulin levels are associated with cognitive performance and CSF amyloid-β and Tau. Additionally, we explore whether any such association differs...

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Vydáno v:J Alzheimers Dis
Hlavní autoři: Geijselaers, Stefan L.C., Aalten, Pauline, Ramakers, Inez H.G.B., De Deyn, Peter Paul, Heijboer, Annemieke C., Koek, Huiberdina L., OldeRikkert, Marcel G.M., Papma, Janne M., Reesink, Fransje E., Smits, Lieke L., Stehouwer, Coen D.A., Teunissen, Charlotte E., Verhey, Frans R.J., van der Flier, Wiesje M., Biessels, Geert Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734123/
https://ncbi.nlm.nih.gov/pubmed/29154275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170522
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