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Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer’s Disease

BACKGROUND: Abnormal insulin signaling in the brain has been linked to Alzheimer’s disease (AD). OBJECTIVE: To evaluate whether cerebrospinal fluid (CSF) insulin levels are associated with cognitive performance and CSF amyloid-β and Tau. Additionally, we explore whether any such association differs...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Geijselaers, Stefan L.C., Aalten, Pauline, Ramakers, Inez H.G.B., De Deyn, Peter Paul, Heijboer, Annemieke C., Koek, Huiberdina L., OldeRikkert, Marcel G.M., Papma, Janne M., Reesink, Fransje E., Smits, Lieke L., Stehouwer, Coen D.A., Teunissen, Charlotte E., Verhey, Frans R.J., van der Flier, Wiesje M., Biessels, Geert Jan
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734123/
https://ncbi.nlm.nih.gov/pubmed/29154275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170522
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