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HDAC inhibitor suppresses proliferation and invasion of breast cancer cells through regulation of miR-200c targeting CRKL

Although histone deacetylase (HDAC) inhibitors have been shown to effectively induce the inhibition of proliferation and migration in breast cancer, the anticancer mechanism remains poorly understood. Our studies show that miR-200c was significantly downregulated in breast cancer cell lines compared...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Pharmacol
Hauptverfasser: Bian, Xuehai, Liang, Zhongxing, Feng, Amber, Salgado, Eric, Shim, Hyunsuk
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733635/
https://ncbi.nlm.nih.gov/pubmed/29155146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.11.008
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