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HDAC inhibitor suppresses proliferation and invasion of breast cancer cells through regulation of miR-200c targeting CRKL

Although histone deacetylase (HDAC) inhibitors have been shown to effectively induce the inhibition of proliferation and migration in breast cancer, the anticancer mechanism remains poorly understood. Our studies show that miR-200c was significantly downregulated in breast cancer cell lines compared...

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Publicado en:Biochem Pharmacol
Main Authors: Bian, Xuehai, Liang, Zhongxing, Feng, Amber, Salgado, Eric, Shim, Hyunsuk
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733635/
https://ncbi.nlm.nih.gov/pubmed/29155146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.11.008
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