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Spinal Cord Cells from Pre-metamorphic Stages Differentiate into Neurons and Promote Axon Growth and Regeneration after Transplantation into the Injured Spinal Cord of Non-regenerative Xenopus laevis Froglets

Mammals are unable to regenerate its spinal cord after a lesion, meanwhile, anuran amphibians are capable of spinal cord regeneration only as larvae, and during metamorphosis, this capability is lost. Sox2/3(+) cells present in the spinal cord of regenerative larvae are required for spinal cord rege...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Méndez-Olivos, Emilio E., Muñoz, Rosana, Larraín, Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733487/
https://ncbi.nlm.nih.gov/pubmed/29326551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00398
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