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Thermo-Sensitive TRP Channels: Novel Targets for Treating Chemotherapy-Induced Peripheral Pain

Abnormal Ca(2+) channel physiology, expression levels, and hypersensitivity to heat have been implicated in several pain states following treatment with chemotherapeutic agents. As members of the Ca(2+) permeable transient receptor potential (TRP), five of the channels (TRPV1-4 and TRPM2) are activa...

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Publicado en:Front Physiol
Autores principales: Nazıroğlu, Mustafa, Braidy, Nady
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733463/
https://ncbi.nlm.nih.gov/pubmed/29326595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01040
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