2-Arylidene Hydrazinecarbodithioates as Potent, Selective Inhibitors of Cystathionine γ-Lyase (CSE)

[Image: see text] Hydrogen sulfide is produced from l-cysteine by the action of both cystathionine γ-lyase (CSE) and cystathionine β-synthase (CBS) and increasingly has been found to play a profound regulatory role in a range of physiological processes. Mounting evidence suggests that upregulation o...

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Bibliografske podrobnosti
izdano v:ACS Med Chem Lett
Main Authors: Bhattacharjee, Abir, Sinha, Antara, Ratia, Kiira, Yin, Liang, Delgado-Rivera, Loruhama, Petukhov, Pavel A, Thatcher, Gregory R. J., Wardrop, Duncan J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2017
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733271/
https://ncbi.nlm.nih.gov/pubmed/29259741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00313
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