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Heterologous Secretory Expression and Characterization of Dimerized Bone Morphogenetic Protein 2 in Bacillus subtilis

Recombinant human Bone Morphogenetic Protein 2 (rhBMP2) has important applications in the spine fusion and ortho/maxillofacial surgeries. Here we first report the secretory expression of biological active dimerized rhBMP2 from Bacillus subtilis system. The mature domain of BMP2 gene was amplified fr...

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Vydáno v:Biomed Res Int
Hlavní autoři: Hanif, Muhammad Umair, Gul, Roquyya, Hanif, Muhammad Imran, Hashmi, Abid Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733156/
https://ncbi.nlm.nih.gov/pubmed/29333457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9350537
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