Multiple Myeloma-Derived Exosomes Regulate the Functions of Mesenchymal Stem Cells Partially via Modulating miR-21 and miR-146a

Exosomes derived from cancer cells can affect various functions of mesenchymal stem cells (MSCs) via conveying microRNAs (miRs). miR-21 and miR-146a have been demonstrated to regulate MSC proliferation and transformation. Interleukin-6 (IL-6) secreted from transformed MSCs in turn favors the surviva...

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Bibliografiske detaljer
Udgivet i:Stem Cells Int
Main Authors: Cheng, Qian, Li, Xin, Liu, Jingru, Ye, Qinmao, Chen, Yanfang, Tan, Sanqin, Liu, Jing
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733127/
https://ncbi.nlm.nih.gov/pubmed/29333170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9012152
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