Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients: a multicenter study from the International Lung Cancer Consortium

BACKGROUND: DNA topoisomerase inhibitors are commonly used for treating small cell lung cancer (SCLC). Tyrosyl-DNA phosphodiesterase (TDP1) repairs DNA damage caused by this class of drugs and may therefore influence treatment outcome. In this study, we investigated whether common TDP1 single nucleo...

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Publicado no:Clin Cancer Res
Principais autores: Lohavanichbutr, Pawadee, Sakoda, Lori C., Amos, Christopher I., Arnold, Susanne M., Christiani, David C., Davies, Michael P.A., Field, John K., Haura, Eric B., Hung, Rayjean J., Kohno, Takashi, Landi, Maria Teresa, Liu, Geoffrey, Liu, Yi, Marcus, Michael W., O’Kane, Grainne M., Schabath, Matthew B., Shiraishi, Kouya, Slone, Stacey A., Tardón, Adonina, Yang, Ping, Yoshida, Kazushi, Zhang, Ruyang, Zong, Xuchen, Goodman, Gary E., Weiss, Noel S., Chen, Chu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732876/
https://ncbi.nlm.nih.gov/pubmed/28974547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1401
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