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Multi-omics analyses of red blood cell reveal antioxidation mechanisms associated with hemolytic toxicity of gossypol

Gossypol is an antiproliferative drug with limited use due to its hemolytic toxicity. In this study, accelerated hemolysis was observed in the cows treated with gossypol. Comparative metabolomics were used to gain responsive pathways in the red blood cell (RBC) to the treatment, which were crossly v...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Tang, Chaohua, Meng, Qingshi, Zhang, Kai, Zhan, Tengfei, Zhao, Qingyu, Zhang, Sheng, Zhang, Junmin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732760/
https://ncbi.nlm.nih.gov/pubmed/29262594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21779
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