Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway

Alpha-ketoglutarate (AKG) is a critical nutritional factor in the maintenance of intestinal homeostasis. However, the relative mechanism of AKG has not been well understood. It was recently shown that the interaction between nuclear factor kappa B (NF-κB)-mediated inflammatory pathway and pregnane X...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: He, Liuqin, Li, Huan, Huang, Niu, Zhou, Xihong, Tian, Junquan, Li, Tiejun, Wu, Jing, Tian, Yanan, Yin, Yulong, Yao, Kang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732704/
https://ncbi.nlm.nih.gov/pubmed/29262538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16875
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