APC loss in breast cancer leads to doxorubicin resistance via STAT3 activation

Resistance to chemotherapy is one of the leading causes of death from breast cancer. We recently established that loss of Adenomatous Polyposis Coli (APC) in the Mouse Mammary Tumor Virus – Polyoma middle T (MMTV-PyMT) transgenic mouse model results in resistance to cisplatin or doxorubicin-induced...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: VanKlompenberg, Monica K., Leyden, Emily, Arnason, Anne H., Zhang, Jian-Ting, Stefanski, Casey D., Prosperi, Jenifer R.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732695/
https://ncbi.nlm.nih.gov/pubmed/29262529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22263
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