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Linking physiologically-based pharmacokinetic and genome-scale metabolic networks to understand estradiol biology

BACKGROUND: Estrogen is a vital hormone that regulates many biological functions within the body. These include roles in the development of the secondary sexual organs in both sexes, plus uterine angiogenesis and proliferation during the menstrual cycle and pregnancy in women. The varied biological...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :BMC Syst Biol
Главные авторы: Sier, Joanna H., Thumser, Alfred E., Plant, Nick J.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732473/
https://ncbi.nlm.nih.gov/pubmed/29246152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0520-3
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