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EBI2 receptor regulates myelin development and inhibits LPC-induced demyelination
BACKGROUND: The G protein-coupled receptor EBI2 (Epstein-Barr virus-induced gene 2) is activated by 7α, 25-dihydroxycholesterol (7α25HC) and plays a role in T cell-dependant antibody response and B cell migration. Abnormal EBI2 signaling is implicated in a range of autoimmune disorders; however, its...
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| Udgivet i: | J Neuroinflammation |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5732472/ https://ncbi.nlm.nih.gov/pubmed/29246262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1025-0 |
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