SOX30 is required for male fertility in mice

Male infertility is a major and growing problem and, in most cases, the specific root cause is unknown. Here we show that the transcription factor SOX30 plays a critical role in mouse spermatogenesis. Sox30-null mice are healthy and females are fertile, but males are sterile. In the absence of Sox30...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Feng, Chun-Wei Allen, Spiller, Cassy, Merriner, Donna J., O’Bryan, Moira K., Bowles, Josephine, Koopman, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732304/
https://ncbi.nlm.nih.gov/pubmed/29247201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17854-5
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