Host species adaptation of TLR5 signalling and flagellin recognition

Toll-like receptor 5 (TLR5) recognition of flagellin instigates inflammatory signalling. Significant sequence variation in TLR5 exists between animal species but its impact on activity is less well understood. Building on our previous research that bovine TLR5 (bTLR5) is functional, we compared huma...

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Publicat a:Sci Rep
Autors principals: Tahoun, Amin, Jensen, Kirsty, Corripio-Miyar, Yolanda, McAteer, Sean, Smith, David G. E., McNeilly, Tom N., Gally, David L., Glass, Elizabeth J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732158/
https://ncbi.nlm.nih.gov/pubmed/29247203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17935-5
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