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Structure–Activity Relationship of Plesiomonas shigelloides Lipid A to the Production of TNF-α, IL-1β, and IL-6 by Human and Murine Macrophages

Plesiomonas shigelloides is a Gram-negative bacterium that is associated with diarrheal disease in humans. Lipopolysaccharide (LPS) is the main surface antigen and virulence factor of this bacterium. The lipid A (LA) moiety of LPS is the main region recognized by target cells of immune system. Here,...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kaszowska, Marta, Wojcik, Marta, Siednienko, Jakub, Lugowski, Czeslaw, Lukasiewicz, Jolanta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5732152/
https://ncbi.nlm.nih.gov/pubmed/29321776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01741
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