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Resetting the yeast epigenome with human nucleosomes
Humans and yeast are separated by a billion years of evolution, yet their conserved histones retain central roles in gene regulation. Here, we “reset” yeast to use core human nucleosomes in lieu of their own – a rare event taking twenty days – which initially only worked with variant H3.1. The cells...
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| Publicado no: | Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5732057/ https://ncbi.nlm.nih.gov/pubmed/29198523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.043 |
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