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Profiling of ribonucleotides and deoxyribonucleotides pools in response to DNA damage and repair induced by methyl methanesulfonate in cancer and normal cells

The absolute and relative pool sizes of deoxyribonucleotides (dRNs) are essential in DNA replication fidelity, DNA damage and repair. We found in this study that although DNA damage induced by methyl methanesulfonate (MMS) seemed similar in cancer (HepG2) and normal (LO2) cells, more extensive alter...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Guo, Jian-Ru, Li, Zheng, Wang, Cai-Yun, Kei Lam, Christopher Wai, Chen, Qian-Qian, Zhang, Wei-Jia, Wai Wong, Vincent Kam, Yao, Mei-Cun, Zhang, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731908/
https://ncbi.nlm.nih.gov/pubmed/29254198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21521
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