The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts

Hydrogen sulfide (H(2)S), generated in the osteoblasts predominantly via cystathionine-γ-lyase (CSE), is bone protective. Previous studies suggested that the onset of bone loss due to estrogen deficiency is associated to decreased levels of H(2)S and blunted gene expression of CSE. However, there ar...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lambertini, Elisabetta, Penolazzi, Letizia, Angelozzi, Marco, Grassi, Francesco, Gambari, Laura, Lisignoli, Gina, De Bonis, Pasquale, Cavallo, Michele, Piva, Roberta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731906/
https://ncbi.nlm.nih.gov/pubmed/29254196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21514
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