The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

The ParB protein forms DNA bridging interactions around parS to condense DNA and earmark the bacterial chromosome for segregation. The molecular mechanism underlying the formation of these ParB networks is unclear. We show here that while the central DNA binding domain is essential for anchoring at...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fisher, Gemma LM, Pastrana, César L, Higman, Victoria A, Koh, Alan, Taylor, James A, Butterer, Annika, Craggs, Timothy, Sobott, Frank, Murray, Heath, Crump, Matthew P, Moreno-Herrero, Fernando, Dillingham, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Structural Biology and Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731820/
https://ncbi.nlm.nih.gov/pubmed/29244022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28086
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