Seasonal Influenza Vaccination of Children Induces Humoral and Cell-Mediated Immunity Beyond the Current Season: Cross-reactivity With Past and Future Strains

BACKGROUND: Influenza viruses gradually accumulate point mutations, reducing the effectiveness of prior immune protection. METHODS: Children aged 9–14 years received 2010–2011 trivalent inactivated influenza vaccine (TIV). Vaccination history, hemagglutination-inhibition (HI) titers, and cell-mediat...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Reber, Adrian J., Kim, Jin Hyang, Coleman, Laura A., Spencer, Sarah M., Chung, Jessie R., Chen, Jufu, Gargiullo, Paul, Sundaram, Maria E., Belongia, Edward A., Shay, David K., Katz, Jacqueline M., Sambhara, Suryaprakash
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731644/
https://ncbi.nlm.nih.gov/pubmed/27571905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw380
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