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Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids

Pyrethroid insecticides exert toxic effects by prolonging the opening of voltage-gated sodium channels. More than 20 sodium channel mutations from arthropod pests and disease vectors have been confirmed to confer pyrethroid resistance. These mutations have been valuable in elucidating the molecular...

詳細記述

保存先:
書誌詳細
出版年:Neurotoxicology
主要な著者: Chen, Mengli, Du, Yuzhe, Nomura, Yoshiko, Zhu, Guonian, Zhorov, Boris S., Dong, Ke
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731473/
https://ncbi.nlm.nih.gov/pubmed/27328896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.06.009
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