PD-L1 and Tumor Infiltrating Lymphocytes Status in Patients with Renal Cell Carcinoma and Sarcomatoid Dedifferentiation

BACKGROUND: The immune profile of sarcomatoid renal cell carcinoma (RCC) (sRCC), including PD-L1 and PD-1 status, has not been well characterized. METHODS: PD-L1, PD-1, CD4, and CD8 immunohistochemical digital analysis was performed on nephrectomy specimens of 118 sRCC and 92 non-sarcomatoid clear c...

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Udgivet i:Cancer
Main Authors: Kawakami, Fumi, Sircar, Kanishka, Rodriguez-Canales, Jaime, Fellman, Bryan M., Urbauer, Diana L., Tamboli, Pheroze, Tannir, Nizar M., Jonasch, Eric, Wistuba, Ignacio I., Wood, Christopher G., Karam, Jose A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731248/
https://ncbi.nlm.nih.gov/pubmed/28832979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30937
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