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SETD2: a complex role in blood malignancy

In this issue of Blood, Mar et al describe the effect of inactivating mutations of the histone methyltransferase (HMT) SETD2 in accelerating leukemia pathogenesis and conferring therapy resistance.(1) Mutations of epigenetic regulators are among the commonest lesions in malignancy. These include mut...

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Dades bibliogràfiques
Publicat a:Blood
Autor principal: Licht, Jonathan D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731090/
https://ncbi.nlm.nih.gov/pubmed/29242204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-811927
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