Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion

Abnormal sickle red blood cell (sRBC) biomechanics, including pathological deformability and adhesion, correlate with clinical severity in sickle cell disease (SCD). Clinical intravenous fluids (IVFs) of various tonicities are often used during treatment of vaso-occlusive pain episodes (VOE), the ma...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Carden, Marcus A., Fay, Meredith E., Lu, Xinran, Mannino, Robert G., Sakurai, Yumiko, Ciciliano, Jordan C., Hansen, Caroline E., Chonat, Satheesh, Joiner, Clinton H., Wood, David K., Lam, Wilbur A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731085/
https://ncbi.nlm.nih.gov/pubmed/28978568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-04-780635
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