Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells

BACKGROUND: This study was aimed at investigating whether metformin can reverse the resistance of ovarian cancer cells to cisplatin and exploring the underlying mechanism. METHODS: Ovarian cancer cell proliferation in vitro was evaluated using a CCK-8 assay. The resistance index of platinum-resistan...

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Vydáno v:BMC Cancer
Hlavní autoři: Du, Juan, Shi, Hui-rong, Ren, Fang, Wang, Jing-lu, Wu, Qing-hua, Li, Xia, Zhang, Rui-tao
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731066/
https://ncbi.nlm.nih.gov/pubmed/29241458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3840-1
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