Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice

BACKGROUND: Intestinal bacteria are known to regulate bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulation of the expression of fibroblast growth factor 19 through intestinal nuclear farnesoid X receptor (FXR). On the other hand, BAs directly regulate the gut microbiota...

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Gepubliceerd in:BMC Biol
Hoofdauteurs: Zheng, Xiaojiao, Huang, Fengjie, Zhao, Aihua, Lei, Sha, Zhang, Yunjing, Xie, Guoxiang, Chen, Tianlu, Qu, Chun, Rajani, Cynthia, Dong, Bing, Li, Defa, Jia, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731064/
https://ncbi.nlm.nih.gov/pubmed/29241453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0462-7
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