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Mechanical signals protect stem cell lineage selection, preserving the bone and muscle phenotypes in obesity

The incidence of obesity is rapidly rising, increasing morbidity and mortality rates worldwide. Associated comorbidities include type 2 diabetes, heart disease, fatty liver disease, and cancer. The impact of excess fat on musculoskeletal health is still unclear, although it is associated with increa...

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Detalhes bibliográficos
Publicado no:Ann N Y Acad Sci
Main Authors: Frechette, Danielle M., Krishnamoorthy, Divya, Pamon, Tee, Chan, M. Ete, Patel, Vihitaben, Rubin, Clinton T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730486/
https://ncbi.nlm.nih.gov/pubmed/28891202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13442
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