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Inhibition of transient potential receptor vanilloid type 1 suppresses seizure susceptibility in the genetically epilepsy‐prone rat

AIMS: Intracellular calcium plays an important role in neuronal hyperexcitability that leads to seizures. One calcium influx route of interest is the transient receptor potential vanilloid type 1 (TRPV1) channel. Here, we evaluated the effects of capsazepine (CPZ), a potent blocker of TRPV1 channels...

詳細記述

保存先:
書誌詳細
出版年:CNS Neurosci Ther
主要な著者: Cho, Sue J, Vaca, Michelle A, Miranda, Clive J, N'Gouemo, Prosper
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730470/
https://ncbi.nlm.nih.gov/pubmed/29105300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12770
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