Ornithine decarboxylase as a therapeutic target for endometrial cancer

Ornithine Decarboxylase (ODC) a key enzyme in polyamine biosynthesis is often overexpressed in cancers and contributes to polyamine-induced cell proliferation. We noted ubiquitous expression of ODC1 in our published endometrial cancer gene array data and confirmed this in the cancer genome atlas (TC...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Hong Im, Schultz, Chad R., Buras, Andrea L., Friedman, Elizabeth, Fedorko, Alyssa, Seamon, Leigh, Chandramouli, Gadisetti V. R., Maxwell, G. Larry, Bachmann, André S., Risinger, John I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730160/
https://ncbi.nlm.nih.gov/pubmed/29240775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189044
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