Alpha2delta-1 in SF1(+) Neurons of the Ventromedial Hypothalamus Is an Essential Regulator of Glucose and Lipid Homeostasis

The central mechanisms controlling glucose and lipid homeostasis are inadequately understood. We show that α2δ-1 is an essential regulator of glucose and lipid balance, acting in steroidogenic factor-1 (SF1) neurons of the ventromedial hypothalamus (VMH). These effects are body weight independent an...

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Опубликовано в: :Cell Rep
Главные авторы: Felsted, Jennifer A., Chien, Cheng-Hao, Wang, Dongqing, Panessiti, Micaella, Ameroso, Dominique, Greenberg, Andrew, Feng, Guoping, Kong, Dong, Rios, Maribel
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730076/
https://ncbi.nlm.nih.gov/pubmed/29212022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.048
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