Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline

IMPORTANCE: Alteration of ex vivo magnetic resonance imaging transverse relaxation is associated with late-life cognitive decline even after controlling for common neuropathologic conditions. However, the underlying neurobiology of this association is unknown. OBJECTIVE: To investigate the associati...

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Publicado no:JAMA Neurol
Main Authors: Yu, Lei, Dawe, Robert J., Boyle, Patricia A., Gaiteri, Chris, Yang, Jingyun, Buchman, Aron S., Schneider, Julie A., Arfanakis, Konstantinos, De Jager, Philip L., Bennett, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729739/
https://ncbi.nlm.nih.gov/pubmed/29084334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2017.2807
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