Towards gene- and gender-based risk estimates in Lynch syndrome; age-specific incidences for 13 extra-colorectal cancer types

BACKGROUND: In Lynch syndrome, inherited mismatch repair (MMR) defects predispose to colorectal cancer and to a wide spectrum of extra-colorectal tumours. Utilising a cohort study design, we aimed to determine the risk of extra-colorectal cancer and to identify yet unrecognised tumour types. METHODS...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Cancer
Prif Awduron: Therkildsen, Christina, Ladelund, Steen, Smith-Hansen, Lars, Lindberg, Lars Joachim, Nilbert, Mef
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Genetics & Genomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729445/
https://ncbi.nlm.nih.gov/pubmed/29065108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.348
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